| Odds via Tonybet | |
| Inter Miami CF vs Tigres UANL | Wednesday, August 20, 2025, 8 PM EDT |
| Inter Miami CF odds | +127 |
| Tigres UANL odds | +179 |
| Draw | +254 |
| Both teams to score | Yes -209, No +148 |
Inter Miami CF vs Tigres UANL Preview and Team News
Inter Miami CF Team News
Inter Miami enjoyed the return of Lionel Messi in their 3-1 home win over the Los Angeles Galaxy in their most recent MLS game and should be close to full strength for this quarterfinal matchup.
The result also allowed Javier Mascherano’s men to bounce back from their 1-4 derby defeat to Orlando City SC, a disappointing outcome given the rivalry between these two Florida-based squads.
However, the loss to Orlando wasn’t a reflection of the Herons’ recent performances, although it did highlight the struggles the team endure when Messi isn’t dictating the play. Inter Miami went undefeated in the Leagues Cup’s first phase, winning two matches in regulation and one in extra time.
Rodrigo De Paul makes sure not to touch Messi in the tackle before snapping his other teammate straight after. 😂
So good. 😂pic.twitter.com/mYD7ParHTX
— Football Tweet ⚽ (@Football__Tweet) August 16, 2025
They’ve also suffered just two losses in their previous 10 outings across all competitions.
The return of Messi and Rodrigo De Paul, two stars who were on the bench in the win over the Galaxy this past weekend, should allow Mascherano to play something close to their strongest XI. The lone absence from the regulars in recent weeks is Federico Redondo, who left the club earlier this month to join Spanish side Elche on a permanent transfer.
Inter Miami CF predicted lineup vs Tigres UANL (4-3-3): Ustari; Weigandt, Falcón, Avilés, Alba; Busquets, De Paul, Segovia; Messi, Suárez, Allende.
Tigres UANL Team News
There’s a strong case to be made that Tigres UANL have been one of the best teams in Mexico in the first weeks of the 2025 Torneo Apertura. Even though their perfect record came to an end with a recent 3-1 loss to Club América, Guido Pizarro’s men have displayed an attractive, explosive brand of soccer that has translated to five wins in seven competitive matches so far.
Their record in the 2025 Leagues Cup hasn’t been perfect either, with two wins (against the Houston Dynamo and San Diego FC) and a defeat (to Los Angeles FC). They followed that up with a 7-0 win over Puebla, once again underlining their biggest strength – an explosive attack.
Termina el encuentro en el Universitario.
Marcador @CEMEXMx.#SiempreContigo 👊 #EstoEsTigres 🐯 pic.twitter.com/FHbOqq8bPu
— Club Tigres 🐯 (@TigresOficial) August 17, 2025
Across their seven competitive fixtures this semester, Tigres have averaged a blistering 2.85 goals per game.
Unfortunately for Pizarro, this attacking firepower hasn’t been backed up by an elite defensive line. The Monterrey giants have conceded at least one goal in five of those seven outings and allowed multiple goals on three occasions.
Tigres are expected to field a very strong XI, although they’ve rarely made changes in competitive encounters this season. They don’t have any key absences outside of Jesus Aneulo (knee).
Tigres UANL predicted lineup vs Inter Miami CF (4-1-4-1): Guzmán; Aquino, Purata, Rómulo, Garza; Gorriarán; Lainez, Correa, Brunetta, Herrera; Ibáñez.
Inter Miami CF vs Tigres UANL Main Match Info
- Date and Kickoff Time: Wednesday, August 20, 2025, 8 PM EDT
- Stadium: Chase Stadium
- Location: Fort Lauderdale, FL, USA
- Last match: Tigres UANL 2:1 Inter Miami CF (August 3, 2024, Leagues Cup)
Inter Miami CF vs Tigres UANL Prediction, Odds
- Pick: Inter Miami CF to win
- Odds: +127 (Tonybet)
- Correct score prediction: Inter Miami CF 2-1 Tigres UANL
It wouldn’t be a stretch to say this matchup brings together one of the most talented teams in the MLS and one of the strongest in Liga MX. However, Inter Miami should have a few advantages ahead of this clash, at least on paper. Perhaps the most important is the return of Messi, who should be an absolute game-changer in the final third alongside Luis Suárez.
Tigres UANL can certainly inflict damage to Inter Miami’s defensive line, as they’ve scored at least one goal in their three encounters of the 2025 Leagues Cup campaign. However, they might not have the defensive depth and quality to slow down the Herons. The Miami-based franchise will have to work hard, but they should be able to secure the victory in what’s shaping up to be an action-packed contest.
Inter Miami CF vs Tigres UANL Betting Tip
- Pick: Over 2.5 total goals and both teams to score
- Odds: -141 (Tonybet)
When looking at what both teams have accomplished in the 2025 Leagues Cup, we can see that each of Tigres’ three matches ended with over 2.5 total goals and both clubs on the scoresheet. The same thing happened in each of the three games Inter Miami played against Liga MX teams, with two of them featuring more than 3.5 total goals.
Given the amount of attacking talent and the lack of defensive ability on either end, it wouldn’t be a stretch to believe we could be in line for another open contest. This is another showdown that could easily deliver more than 2.5 goals, with both sides finding the back of the net. Five of Tigres’ last six competitive fixtures have seen both squads score.
Inter Miami CF vs Tigres UANL: Where to Watch (Canada)
- MLS Season Pass
- Amazon Prime Video
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