Moneyline PickInter Miami to Win (+215)
Player PropLionel Messi to Score (+112)
Same Game ParlayInter Miami to Win + Lionel Messi to Score + Over 2.5 Goals (+425)
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Los Angeles FC vs Inter Miami CF Main Match Info

Los Angeles FC vs Inter Miami CF Moneyline Prediction

Los Angeles hold the head-to-head edge (three wins in five encounters), but the dynamic has changed since Lionel Messi’s arrival. In the last three meetings, Inter Miami have beaten them twice, including a 3-1 victory in the Concacaf Champions Cup.

LAFC’s pressing can force turnovers, but it can also leave space behind their midfield line. Against the Herons, a single broken press can become a high-quality chance.

The hosts should benefit from playing on familiar turf. However, given Messi’s factor and influence (35 goals + 28 assists), Miami are favoured to win this match. 

Los Angeles FC vs Inter Miami CF Player Prop

In the 2025 MLS season, Messi led Inter Miami in shots with 5.4 per 90 minutes and shots on target with 2.4. He also topped the league with 35 goals in 34 matches, along with 28 assists.

Los Angeles are expected to play aggressively at home, a style that can leave exploitable space behind. Even at 38, Messi remains the league’s most dangerous player between the lines, capable of turning one broken press into a shot or a cutback chance.

Despite injury worries, he is fit and most recently scored against Barcelona SC in a friendly. As such, the Argentine is a strong candidate to get on the scoresheet. 

Los Angeles FC vs Inter Miami CF Same Game Parlay

Inter Miami to Win: LAFC are formidable at home, but Inter Miami are the reigning champions. We expect a tough game, with the visitors claiming a narrow win.

Lionel Messi to Score: Messi led MLS with 35 goals last season. As the Herons’ talisman, he is likely to score in the opener.

Over 2.5 Goals: Both teams are known for their prolific offence. Miami netted 81 goals in the regular season, while Los Angeles recorded 65. This matchup has all the ingredients for a high-scoring contest.

Los Angeles FC vs Inter Miami CF Team News

Los Angeles FC Team News 

LAFC come into the opening MLS weekend with confidence after a 1-6 first-leg win over Real España in the Concacaf Champions Cup. In that encounter, they generated 3.9 xG from 14 shots (eight on target) while allowing 0.78 xGA. Moreover, Denis Bouanga hit a hat-trick, and Son Heung-Min produced three assists.

Tactically, the Black and Gold create chances through pace and combination play in the final third, drawing contact in the box. When they concede, it tends to be from game-state dips. Even in the 1-6 win, their lone concession came in the second half when intensity shifted. 

Igor Jesus is out with a knee injury, while centre-back Aaron Long is also sidelined. Jeremy Ebobisse is questionable. 

Inter Miami CF Team News

Before the start of the season, Inter Miami saw Sergio Busquets and Jordi Alba retire, while Fafà Picault moved to Atlanta United. However, the core of the squad remains intact. Luis Suárez (10 goals) has signed a contract extension that keeps him at the club through the 2026 season.

In 2025, Inter Miami led MLS in scoring with 81 goals and conceded around 1.62 goals per game. Tactically, coach Javier Mascherano has his side set up to attack through the centre, which produces plenty of shots inside the box but also exposes them to counters.

Lionel Messi suffered a hamstring strain during preseason but has since returned to full training. As for absentees, Ryan Sailor is out, and Sergio Reguilon is listed as questionable.

Los Angeles FC vs Inter Miami CF: Where to Watch (Canada) 

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