Moneyline PickManchester United (+146)
Player PropBenjamin Šeško to score anytime (+195)
Same Game ParlayBoth teams to score + Over 3.5 total goals + Šeško to score anytime (+400)
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Manchester United vs Newcastle United Main Match Info

Manchester United vs Newcastle United Moneyline Prediction

On paper, it’s not entirely clear whether Manchester United are the favourites ahead of this matchup. 

They’ll be missing several key players on both sides of the ball, and the absence of the creativity provided by Bryan Mbeumo and Bruno Fernandes, along with the pace of Amad Diallo, could prove to be a massive issue for the Red Devils.

However, they’ll be facing a Newcastle United team that have endured their fair share of struggles away from home this season (W1, D3, L4). Plus, a lack of depth on the defensive end is also a massive issue for the Magpies

They might be without their goalkeeper, their two best centre-backs, and their two options at right-back.

At the end of the day, this battle between two depleted squads will be decided by small margins. Newcastle’s road woes are just too big to ignore, and Manchester United have the advantage of being at home (W4, D2, L2), which should be enough for them to win.

Manchester United vs Newcastle United Player Prop

Šeško hasn’t had his best season in 2025-26, and he’s found the back of the net just twice in 13 Premier League outings. Man United will be missing Mbeumo and Fernandes, meaning the team will rely even more on the likes of Matheus Cunha and Šeško to step up in the final third. 

Look for Šeško to deliver against a Newcastle side that will be heavily depleted defensively.

Manchester United vs Newcastle United Same Game Parlay

Our three-leg parlay backs a high-scoring game, a scenario that looks entirely plausible when assessing both teams’ recent form. Manchester United have struggled to keep clean sheets all season long, while Newcastle’s lack of defensive depth could further complicate matters on their trip to Old Trafford.

Both sides could very well find the back of the net as well, as that has happened in nine of United’s last 10 league encounters and in four of the Magpies’ previous five across all competitions.

Last but not least, Šeško looks like a good bet to score if Man Utd are to win here. The Slovenia international has endured a rocky start to his Old Trafford tenure, but he must step up for the Red Devils, especially given the club’s lack of depth in the final third.

Manchester United vs Newcastle United Team News

Manchester United Team News 

Manchester United will be without two key attacking players, as Bryan Mbeumo and Amad Diallo are away on AFCON duty representing Cameroon and the Ivory Coast, respectively. Noussair Mazraoui is also on AFCON duty with Morocco.

Star playmaker Bruno Fernandes is out with a hamstring injury and isn’t expected back until mid-January at the earliest, while Kobbie Mainoo (calf) is also unavailable. Harry Maguire is sidelined with a hamstring injury, and Matthijs de Ligt is doubtful due to a back problem.

Newcastle United Team News

Newcastle are uncertain about the availability of Nick Pope. The starting goalkeeper is dealing with a groin injury and is considered a game-time call, but if he’s unable to play, then Aaron Ramsdale would get another start between the posts.

The team are depleted defensively. Dan Burn (ribs), Valentino Livramento (knee), Kieran Trippier (hamstring), Emil Krafth (knee), and Sven Botman (back) are all out. Backup striker Will Osula (ankle) is also sidelined.

Manchester United vs Newcastle United: Where to Watch (Canada) 

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